Rabbit anti-LAG3 Monoclonal Antibody
| Catalog number: | B2015578 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 10 l |
| Molecular Weight or Concentration: | N/A |
| Supplied as: | Solution |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | 2-8C |
| Keywords: | CD antigen CD223;CD223;LAG-3;Ly66;lymphocyte activation gene 3 protein |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
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- FDA approves anti-LAG3 checkpoint Nat Biotechnol. 2022 May;40(5):625.
- Bae J, Accardi F, Hideshima T, Tai YT, Prabhala R, Shambley A, Wen K, Rowell S, Richardson PG, Munshi NC, Anderson KC. Targeting LAG3/GAL-3 to overcome immunosuppression and enhance anti-tumor immune responses in multiple myeloma Leukemia. 2022 Jan;36(1):138-154.
- Andrews LP, Cillo AR, Karapetyan L, Kirkwood JM, Workman CJ, Vignali DAA. Molecular Pathways and Mechanisms of LAG3 in Cancer Therapy Clin Cancer Res. 2022 Dec 1;28(23):5030-5039.
- Mulholland M, Kritikou E, Katra P, Nilsson J, Bjrkbacka H, Lichtman AH, Rodriguez A, Engelbertsen D. LAG3 Regulates T Cell Activation and Plaque Infiltration in Atherosclerotic Mice JACC CardioOncol. 2022 Dec 20;4(5):635-645.
- Lauder SN, Vanhaesebroeck B, Gallimore A. Sequential targeting of PI3K and LAG3 as an effective anti-cancer approach Br J Cancer. 2021 Aug;125(4):467-469.
- Pang XQ, Li X, Zhu WH, Huang RK, Mo ZS, Huang ZX, Zhang Y, Xie DY, Gao ZL. LAG3(+) erythroid progenitor cells inhibit HBsAg seroclearance during finite pegylated interferon treatment through LAG3 and TGF- Antiviral Res. 2023 May;213:105592.
- Warren PD, Dodson MS, Smith MH, Landowski TH, Palting JD, Towne P. High-Resolution Epitope Mapping and Affinity Binding Analysis Comparing a New Anti-Human LAG3 Rabbit Antibody Clone to the Commonly Used Mouse 17B4 Clone Antibodies (Basel). 2022 Sep 21;11(4):60.
- Ascione A, Arenaccio C, Mallano A, Flego M, Gellini M, Andreotti M, Fenwick C, Pantaleo G, Vella S, Federico M. Development of a novel human phage display-derived anti-LAG3 scFv antibody targeting CD8(+) T lymphocyte exhaustion BMC Biotechnol. 2019 Oct 17;19(1):67.
