Procalcitonin Antibody (PCT Antibody)

Procalcitonin Antibody (PCT Antibody)

The Procalcitonin (PCT) Antibody is a high-affinity polyclonal immunoreagent designed for the detection of human procalcitonin, a key biomarker in the diagnosis and monitoring of systemic bacterial infections and sepsis. Purified via protein A Sepharose chromatography, this antibody offers high specificity and minimal cross-reactivity, making it ideal for use in ELISA, Western blotting, and other immunoassay formats.

Procalcitonin levels rise significantly in response to bacterial endotoxins, making this antibody a valuable tool for researchers studying inflammatory pathways, acute phase responses, and critical care biomarkers. Its performance has been referenced in multiple peer-reviewed studies focused on pulmonary inflammation, osteomyelitis, and severe pneumonia, underscoring its relevance in translational and clinical research.

Supplied as a liquid solution with 0.05% sodium azide, the antibody is stable and ready to use in both exploratory and high-throughput workflows.

Key benefits:

• Specific to human procalcitonin with minimal background

• Affinity purified for high purity and reproducibility

• Validated in multiple peer-reviewed clinical studies

• Compatible with ELISA, WB, and other immunoassays

• Supports research in infectious disease and critical care biomarkers

Products are for in vitro research use only (RUO).

References

• Cosma S, Borella F, Carosso A, Ingala A, Fassio F, Robba T, Maina A, Bertero L, Benedetto C. Osteomyelitis of the pubic symphysis caused by methicillin-resistant Staphylococcus aureus after vaginal delivery: a case report and literature review. BMC Infect Dis . 2019 Nov 8;19(1):952.
• Chalmers S, Khawaja A, Wieruszewski PM, Gajic O, Odeyemi Y. Diagnosis and treatment of acute pulmonary inflammation in critically ill patients: The role of inflammatory biomarkers. World J Crit Care Med . 2019 Sep 11;8(5):59-71.
• Ge YL, Zhang Q, Wang MH, Li LQ, Fu AS, Liu CH, Zhang HF, Li WQ, Chen Y, Zhang S, Hao C, Zhang C, Zhu XY. Negative (1,3)–D-glucan and Elevated White Blood Cells Combined Procalcitonin Masquerading as Severe Pneumonia Eventually Diagnosed as Invasive Pulmonary Aspergillosis Proven by Bronchoalveolar Lavage Fluid Culture in a Diabetes Patient: a Case Report and Literature Review. Clin Lab . 2019 Aug 1;65(8).
• Jun J, Lee SR, Lee JY, Choi MJ, Noh JY, Cheong HJ, Kim WJ, Song JY. Pneumonitis and concomitant bacterial pneumonia in patients receiving pembrolizumab treatment: Three case reports and literature review. Medicine (Baltimore) . 2019 Jun;98(25):e16158.
• Leppniemi A, Tolonen M, Tarasconi A, Segovia-Lohse H, Gamberini E, Kirkpatrick AW, Ball CG, Parry N, Sartelli M, Wolbrink D, van Goor H, Baiocchi G, Ansaloni L, Biffl W, Coccolini F, Di Saverio S, Kluger Y, Moore E, Catena F. 2019 WSES guidelines for the management of severe acute pancreatitis. World J Emerg Surg . 2019 Jun 13;14:27.