Human CLIC4 Protein
| Catalog number: | B2011975 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 100 g |
| Molecular Weight or Concentration: | 0.5 mg/mL |
| Supplied as: | Solution |
| Applications: | molecular tool for various biochemical applications |
| Storage: | -20 C |
| Keywords: | CLIC 4, Chloride intracellular channel protein 4 protein, huH1 protein, CLIC-4 protein, DKFZp566G223 protein, MTCLIC protein, CLIC-4, CLIC 4 protein, P64h1 protein, CLIC4L protein, CLIC4, H1 protein, FLJ38640 protein |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Yokoyama R, Kojima H, Takai R, Ohta T, Maeda H, Miyashita K, Mutoh M, Terasaki M. Effects of CLIC4 on Fucoxanthinol-Induced Apoptosis in Human Colorectal Cancer Cells Nutr Cancer. 2021;73(5):889-898.
- Abdul-Salam VB, Russomanno G, Chien-Nien C, Mahomed AS, Yates LA, Wilkins MR, Zhao L, Gierula M, Dubois O, Schaeper U, Endruschat J, Wojciak-Stothard B. CLIC4/Arf6 Pathway Circ Res. 2019 Jan 4;124(1):52-65.
- Argenzio E, Klarenbeek J, Kedziora KM, Nahidiazar L, Isogai T, Perrakis A, Jalink K, Moolenaar WH, Innocenti M. Profilin binding couples chloride intracellular channel protein CLIC4 to RhoA-mDia2 signaling and filopodium formation J Biol Chem. 2018 Dec 14;293(50):19161-19176.
- Argenzio E, Innocenti M. The chloride intracellular channel protein CLIC4 inhibits filopodium formation induced by constitutively active mutants of formin mDia2 FEBS Lett. 2020 Jun;594(11):1750-1758.
- Suh KS, Crutchley JM, Koochek A, Ryscavage A, Bhat K, Tanaka T, Oshima A, Fitzgerald P, Yuspa SH. Reciprocal modifications of CLIC4 in tumor epithelium and stroma mark malignant progression of multiple human cancers Clin Cancer Res. 2007 Jan 1;13(1):121-31.
- Wang B, Zheng J, Chen Q, Wu C, Li Y, Yu XY, Liu B, Liang C, Liu SB, Ding H, Wang S, Xue T, Song D, Lei Z, Amin HM, Song YH, Zhou J. CLIC4 abrogation promotes epithelial-mesenchymal transition in gastric cancer Carcinogenesis. 2020 Jul 10;41(6):841-849.
- Wasson CW, Ross RL, Morton R, Mankouri J, Del Galdo F. The intracellular chloride channel 4 (CLIC4) activates systemic sclerosis fibroblasts Rheumatology (Oxford). 2021 Sep 1;60(9):4395-4400.
- Yokoyama R, Kushibiki A, Yamada S, Kubota A, Kojima H, Ohta T, Hamada J, Maeda H, Mutoh M, Terasaki M. Requirement of CLIC4 Expression in Human Colorectal Cancer Cells for Sensitivity to Growth Inhibition by Fucoxanthinol Cancer Genomics Proteomics. 2022 Jul-Aug;19(4):428-444.
- Suh KS, Mutoh M, Gerdes M, Yuspa SH. CLIC4, an intracellular chloride channel protein, is a novel molecular target for cancer therapy J Investig Dermatol Symp Proc. 2005 Nov;10(2):105-9.
