5-TAMRA Cadaverine

5-TAMRA Cadaverine Catalog B2011357 (1 mg)

5-TAMRA Cadaverine is a fluorescent amine-reactive tag that integrates a rhodamine-based fluorophore (5-TAMRA) tethered to cadaverine, enabling direct conjugation to biomolecules such as peptides, proteins, and antibodies. Supplied as a 1 mg lyophilized powder (Catalog B2011357), this high-purity reagent offers bright red fluorescence, making it an excellent tool for tracking molecular interactions in imaging, flow cytometry, and advanced biochemical assays.

Developed with biotechnology-grade standards, 5-TAMRA Cadaverine facilitates reliable fluorescent labeling via amine coupling while maintaining minimal nonspecific binding and high photostability. Its lyophilized format ensures long-term storage at 20 C with maintained activity. This flexibility supports use across a range of conjugation workflows, from research-scale labeling to high-throughput assay development. Custom bulk orders are offered to accommodate long-term or large-volume projects.

Why researchers choose this product:

• Bright red fluorescence via 5-TAMRA, ideal for imaging and detection
• Amine-reactive cadaverine moiety enables efficient conjugation to biomolecules
• Biotech-grade purity ensures minimal background and reproducible results
• Lyophilized format allows long-term storage and precise handling
• Bulk supply available for extensive labeling campaigns or scale-up

Indication for Use:
This product is for Research Use Only (RUO). It is not intended for diagnostic, therapeutic, or clinical use.

References:

• 1: Gibbs NM, Su SH, Lopez-Nieves S, Mann S, Alban C, Maeda HA, Masson PH. Cadaverine regulates biotin synthesis to modulate primary root growth in Arabidopsis Plant J. 2021 Sep;107(5):1283-1298.
• 2: Moon YM, Yang SY, Choi TR, Jung HR, Song HS, Han YH, Park HY, Bhatia SK, Gurav R, Park K, Kim JS, Yang YH. Enhanced production of cadaverine by the addition of hexadecyltrimethylammonium bromide to whole cell system with regeneration of pyridoxal-5-phosphate and ATP Enzyme Microb Technol. 2019 Aug;127:58-64.
• 3: Kim JH, Kim J, Kim HJ, Sathiyanarayanan G, Bhatia SK, Song HS, Choi YK, Kim YG, Park K, Yang YH. Biotransformation of pyridoxal 5-phosphate from pyridoxal by pyridoxal kinase (pdxY) to support cadaverine production in Escherichia coli Enzyme Microb Technol. 2017 Sep;104:9-15.
• 4: Verhage L. Smelly business Cadaverine modulates root growth by inhibiting biotin synthesis Plant J. 2021 Sep;107(5):1281-1282.
• 5: Brito LF, Irla M, Nrdal I, Le SB, Delpine B, Heux S, Brautaset T. Evaluation of Heterologous Biosynthetic Pathways for Methanol-Based 5-Aminovalerate Production by Thermophilic Bacillus methanolicus Front Bioeng Biotechnol. 2021 Jun 28;9:686319.
• 6: Han YH, Kim HJ, Choi TR, Song HS, Lee SM, Park SL, Lee HS, Cho JY, Bhatia SK, Gurav R, Park K, Yang YH. Improvement of cadaverine production in whole cell system with bakers yeast for cofactor regeneration Bioprocess Biosyst Eng. 2021 Apr;44(4):891-899.
• 7: Ikeda N, Miyamoto M, Adachi N, Nakano M, Tanaka T, Kondo A. Direct cadaverine production from cellobiose using -glucosidase displaying Escherichia coli AMB Express. 2013 Nov 8;3(1):67.
• 8: Rui J, You S, Zheng Y, Wang C, Gao Y, Zhang W, Qi W, Su R, He Z. High-efficiency and low-cost production of cadaverine from a permeabilized-cell bioconversion by a Lysine-induced engineered Escherichia coli Bioresour Technol. 2020 Apr;302:122844.
• 9: Wang X, Guo X, Wang J, Li H, He F, Xu S, Chen K, Ouyang P. Ameliorating end-product inhibition to improve cadaverine production in engineered Escherichia coli and its application in the synthesis of bio-based diisocyanates Synth Syst Biotechnol. 2021 Sep 14;6(4):243-253.
• 10: Wang J, Lu X, Ying H, Ma W, Xu S, Wang X, Chen K, Ouyang P. A Novel Process for Cadaverine Bio-Production Using a Consortium of Two Engineered Escherichia coli Front Microbiol. 2018 Jun 19;9:1312.